Место работы автора, адрес/электронная почта: ГАУ РС (Я) Республиканская больница N 1 - Национальный центр медицины ; 677008, г. Якутск, ул. Сергеляхское шоссе, 4 ; e-mail: verprok@yandex.ru ; https://rb1ncm.ru/
Область научных интересов: Педиатрия
Количество страниц: 6 с.
Клинико-микробиологическая характеристика локальных форм гнойно-воспалительных заболеваний новорожденных / В. Б. Егорова, В. П. Афанасьева, Я .А. Мунхалова [и др.] // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия "Медицинские науки". – 2021. – N 4 (25). – C. 48-53. – DOI: 10.25587/SVFU.2021.25.4.007
DOI: 10.25587/SVFU.2021.25.4.007
Количество страниц: 6 с.
Congenital hypothyroidism (CH), a violation of the secretion of thyroid hormones, is one of the most common congenital diseases of the endocrine glands, leading to severe disability without timely diagnosis and treatment. The incidence of CH ranges from 1 case per 4000-5000 newborns in Europe and North America to 1 case per 6000-7000 newborns in Japan. In addition, in children with the Down syndrome, the risk of developing CH is 35 times higher compared to the general population. In girls, the disease occurs 2-2.5 times more often than in boys. Currently, there is no doubt that CH in its prevalence and medico-social significance occupies an important place among childhood endocrine pathologies. The neonatal screening program for the determination of congenital hypothyroidism allows for early diagnosis and adequate treatment of children, which can help to avoid complications associated with a lack of hormones. Most newborns have no hypothyroidism clinic at birth because maternal hormones even in late pregnancy penetrate the placenta, and cord blood contains from 25 to 50 % of hormones of maternal origin. Most often, the clinical picture of congenital hypothyroidism in newborns develops gradually and is not clearly manifested in all children in the neonatal period. If obvious symptoms are noted already in the first week of life, a severe form of hypothyroidism due to aplasia or severe thyroid hypoplasia can be suspected. Hypothyroidism due to moderate hypoplasia, ectopia of the thyroid gland, or hormonal abnormalities may not have clinical manifestations during the neonatal period and may even manifest after 2-6 years of age. Screening programs may skip cases of congenital hypothyroidism (early discharge, laboratory error, severe illness, prematurity, low birth weight, transfer to another hospital, etc.), therefore, with clinical signs of hypothyroidism, a second hormonal examination is necessary. This article presents a clinical case of congenital hypothyroidism in a newborn baby in the Sakha Republic (Yakutia)
Егорова, В. Б. Клинический случай внутри врожденного гипотиреоза у новорожденного / В. Б. Егорова, В. П. Афанасьева, Н. А. Потапова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2020. — N 4 (21). — С. 35-39.
DOI: 10.25587/SVFU.2020.21.4.006
Количество страниц: 6 с.
Егорова, В. Б. Клинический случай врождённого гипотиреоза у новорождённого / В. Б. Егорова, В. П. Афанасьева, Н. А. Потапова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия "Медицинские науки". – 2020. – N 4 (21). – C. 35-39. – DOI: 10.25587/SVFU.2020.21.4.006
DOI: 10.25587/SVFU.2020.21.4.006