Место работы автора, адрес/электронная почта: Северо-Восточный федеральный университет им. М. К. Аммосова, Медицинский институт ; 677016, г. Якутск, ул. Ойунского, 27 ; e-mail: tya.nikolaeva@s-vfu.ru ; https://www.s-vfu.ru
Республиканская больница N 2 - Центр экстренной медицинской помощи, Региональный сосудистый центр ; 677005, г. Якутск, ул. Петра Алексеева, 83А ; e-mail: tyanic@mail.ru ; http://rb2cemp.ru/
Ученая степень, ученое звание: д-р мед. наук
Область научных интересов: Цереброваскулярная патология в Якутии, вопросы вклада генетических факторов в развитие ишемического и геморрагического инсульта
ID Автора: SPIN-код: 6180-7862, РИНЦ AuthorID: 129834
Деятельность: Работала врачом-неврологом Поликлиники N 1 г. Якутска, Неврологического отделения Якутской республиканской клинической больницы. С 1989 г. работает в ЯГУ.
Количество страниц: 4 с.
- Общественные науки. Образование > Народное образование. Воспитание. Обучение. Организация досуга > Профессиональное и среднее специальное образование,
- Общественные науки. Образование > Народное образование. Воспитание. Обучение. Организация досуга > Высшее образование. Высшая школа. Подготовка научных кадров,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Неврология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Неврология,
- НАУКА ЯКУТИИ > ОБЩЕСТВЕННЫЕ НАУКИ > Народное образование. Воспитание. Обучение. Организация досуга > Высшее образование. Высшая школа. Подготовка научных кадров,
- НАУКА ЯКУТИИ > ОБЩЕСТВЕННЫЕ НАУКИ > Народное образование. Воспитание. Обучение. Организация досуга > Профессиональное и среднее специальное образование.
The ability to conduct the lumbar puncture is one of the most important practical skills in Neurology. The lumbar puncture is used widely for diagnostic and therapeutic objectives. In addition to the technical difficulties, young physicians often face the psychological problems related to the uncertainty and fear of the procedure failing. Interactive teaching methods are an important step in the physician training. Lecturers at the Department of Neurology and Psychiatry hold the lumbar puncture training classes in the Simulation Center of the Medical Institute, M.K. Ammosov North-Eastern Federal University. The training is conducted on the lumbar puncture simulator which can provide the visual and tactile sensations identical to those obtained in clinical practice. The classes are held with clinical residents, interns, students in the classroom of basic practical skills. The practice consists of three stages: introduction, practical part and discussion. In the practical part the lecturer demonstrates the lumbar puncture technique on the simulator. Then the student conducts manipulation under the lecturer’s supervision. During the manipulation, the lecturer points out errors to the student. In case of an unsuccessful attempt, the procedure must be repeated. The lumbar puncture skill is counted if the procedure has been made by the student himself. In the third part of the practice, the group led by the lecturer discusses the practical work, analyzes the errors and debates the future actions. Thus, the interactive learning is a productive method in the higher medical education system. The simulator training skills improve the professional competence of the physician and it is necessary for the further clinical activities
Николаева, Т. Я. Интерактивные методы обучения в неврологии / Т. Я. Николаева, С. А. Чугунова, Э. Э. Конникова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2017. — N 1 (06). — С. 55-58.
Количество страниц: 4 с.
- Математика. Естественные науки > Природа. Охрана окружающей среды,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Природа. Охрана окружающей среды.
The article presents literature data on the interaction between the influence of technogenic pollution of the environment (pollutants) and development of stroke in different countries. In recent years, prevention, diagnosis and treatment of the stroke has significantly improved, but there is a significant difference in epidemiological indicators in different countries and regions of Russia. The difference in morbidity and mortality from cerebrovascular diseases can be explained by the environmental situation in the studied regions. In the polluted areas, there is a high morbidity and mortality from cerebrovascular diseases and stroke. Even a short-term increase in the level of pollutants in the air increases the number of hospitalizations for stroke. Russian studies of the relationship betweenthe ecological situation and stroke was conducted in the industrial cities of Yaroslavl and Ufa. The studies show a clear link between air pollution and different pollutants with the severity of stroke. The obtained data testify to the impact of environmental pollution on the growth of morbidity and mortality from ischemic stroke but not hemorrhagic. The negative effect of pollutants was somewhat more pronounced in the cold season. The study of the influence of air pollution on epidemiological indicators of stroke will allow us to develop effective methods of primary prevention in polluted regions
Николаева, Т. Я. Экологические аспекты в изучении эпидемиологии инсульта / Т. Я. Николаева, А. А. Семенов // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2017. — N 4 (09). — С. 69-72.
Количество страниц: 6 с.
Venous stroke is one of the rare forms of acute cerebral circulation disorders. The disease develops due to the thrombosis of the brain veins or sinuses. The venous stroke causes are conditions associated with thrombophilia including the antiphospholipid syndrome, pregnancy, sepsis, oral contraceptive use, malignant neoplasms and other diseases. In some cases, the venous stroke cause remains unclarified. The venous stroke etiological factor establishing requires a multifaceted examination, including genetic screening for congenital thrombophilia. This article presents the clinical case of the venous stroke in a young patient. The disease developed in the postpartum period. The clinical manifestations were characterized by the presence of cerebral, meningeal symptoms and convulsive syndrome. The laboratory examination revealed thrombocytosis, hypochromic anemia. The brain magnetic resonance imaging with venography diagnosed the sagittal sinus thrombosis and small area of cytotoxic edema. Examination of somatic status did not reveal the signs of systemic, infectious, oncological diseases. The genetic study was carried out to identify the polymorphism variants, including 677 C / T of MTHFR gene, 1298AC of MTHFR gene, 66 AG of MTRR gene, 2756 AG of MTR gene, 20210 GA of F2 gene, 1691 GA of F5 gene. This genetic screening did not reveal the risk factors for congenital thrombophilia. We carried out the anticoagulant, antiplatelet, anti-edematous, neuroprotective therapy, and the neurological symptoms were regressed, thrombocytosis index decreased, the diameter of the sagittal sinus thrombus decreased. In this clinical case, the cerebral sinus thrombosis developed due to the changes in the hormonal status and blood coagulation properties on the background of pregnancy and childbirth. In clinical practice, it is necessary to pay special attention to the possible risks of cerebral sinuses and veins thrombosis during pregnancy and postpartum period. In addition, it is necessary to examine the carriage of genetic congenital thrombophilia risk factors in young venous stroke patients
Венозный инсульт у пациентки молодого возраста: клиническое наблюдение / С. А. Чугунова, Т. Я. Николаева, А. В. Игнатьева [и другие] // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2017. — N 4 (09). — С. 121-125.
Количество страниц: 10 с.
Parkinson’s disease is one of the most common neurodegenerative disease and found in all countries of the world. The average prevalence of the disease varies from 120 to 180 per 100 thousand population. Parkinson’s disease is disease of the elderly: if up to 45 years, it almost does not occur, then after 60 years of Parkinson’s disease suffers 1-2% of the population, and after 85 years - 3-5%. According to the latest WHO data, in the world of Parkinson’s disease affects more than 4 million people. This indicator will continue to grow and by 2030 will amount to 9 million people. The disease was first described in 1817 by the English surgeon James Parkinson in his “Essay on the Shaking Palsy”. However, until recently, in spite of a breakthrough science are not fully clarified the etiology and pathogenesis of the disease. Parkinson’s disease currently is considered as multifactorial disease and thus, it is intended multifactorial causes, including genetic and environmental factors. However, significant factors affecting the development of the disease is not currently identified. In recent years, widely it begins to studyof impact bowel microbiocenosis on the development of neurodegenerative diseases, including and Parkinson’s disease. The article describes the latest data of the scientific literature on the contribution of genetic, demographic and environmental factors in the development of Parkinson’s disease and discusses the current pathogenic mechanisms
Современные представления об этиологии и патогенезе болезни Паркинсона (обзор) / А. А. Таппахов, Т. Я. Николаева // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2016. — N 2 (03). — С. 19-27.
Количество страниц: 4 с.
- Краеведение. Археология. География. Биографии. История > Биографии. Генеалогия. Геральдика,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Ортопедия. Хирургия. Офтальмология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Ортопедия. Хирургия. Офтальмология,
- НАУКА ЯКУТИИ > КРАЕВЕДЕНИЕ. ГЕОГРАФИЯ. БИОГРАФИИ. ИСТОРИЯ > Биографии. Генеалогия. Геральдика.
Николаева, Т. Я. 75 лет профессору М. П. Гоголеву. 75 ear of professor M. P. Gogolev / Т. Я. Николаева // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2016. — N 4 (05). — С. 33-35.
Количество страниц: 4 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Эпидемиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина.
Results of epidemiological research of prevalence of an epilepsy among the population senior 14 years of a city of Yakutsk Republic Sakha (Yakutia) are resulted. The conducted research has allowed to receive a complex clinical-epidemiological picture of an epilepsy among republic urban population. Prevalence of an epilepsy here was slightly more low, than among agricultural population. Observable distinctions of prevalence of an epilepsy at men and women have not reached authentic values. The analysis of current therapy has shown low efficiency of the received treatment, insufficient use of modern antiepileptic drug
Эпидемиология эпилепсии среди взрослого населения г. Якутска / Г. Н. Бирюкбаева, А. А. Николаева, Е. В. Винокуров [и другие] // Якутский медицинский журнал. — 2010. — N 1 (29). — С. 26-28.
Количество страниц: 8 с.
Acetylsalicylic acid is one of the most widely prescribed antiplatelet drugs in medicine. For the evaluation of the effectiveness of antiplatelet drugs in clinical practice, laboratory testing is used as an aggregometry method. This method makes it possible to estimate the aggregation activity of platelets in persons under treatment with acetylsalicylic acid preparations. High aggregation activity of platelets is thought to be associated with aspirin resistance, a state in which acetylsalicylic acid preparations are unable to prevent excess platelet aggregation and platelet events. This is due to the early increase in neurological deficits and the repeated development of ischemic stroke in patients in the acute period. A large number of factors, including race, sex and the carrying of certain genetic polymorphisms, influence the development of aspirin resistance. According to some sources, low aggreragative activity of platelets means increased sensitivity to the drug, which may lead to complications with aspirin, haemorrhagic events of various localizationsin particular. A study of the aggregate activity of platelets in the population will make it possible to avoid unnecessary aspirin intake as a primary and secondary prevention of cardiovascular diseases
Эверстова, Т. Я. Проблемы аспиринорезистентности во вторичной профилактике ишемического инсульта / Т. Е. Эверстова, Т. Я. Николаева // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2021. — N 1 (22). — С. 33-40.
DOI: 10.25587/SVFU.2021.22.1.005
Количество страниц: 8 с.
The article analyzes the performance of the Neurological Department for patients with acute cerebrovascular accidents at the Regional Vascular Center for 10 years (2011-2020). The opening of the Regional Vascular Center and primary vascular departments made it possible to reduce significantly the rates of mortality and disability from stroke in the republic. The modern technologies introduced there for providing treatment to patients with stroke reduced the mortality from hemorrhagic stroke from 23.8% in 2010 to 13.4% in 2019, with the indicator increased in 2020 to 23.5%, and from subarachnoid hemorrhage - from 40.9% in 2010 to 16.1% in 2020. The proportion of the patients capable of self-care increased from 55.8% to 67.2%. The facilities at the Regional Vascular Center allow 100% inpatient admission of the patients living in Yakutsk City
Николаева, Т. Я. Анализ показателей работы неврологического отделения регионального сосудистого центра г. Якутска за 10 лет / Т. Я. Николаева, С. Ф. Шадрина, Т. С. Егорова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2021. — N 1 (22). — С. 57-63.
DOI: 10.25587/SVFU.2021.22.1.008
Количество страниц: 2 с.
90 лет выдающемуся сыну якутского народа П. А. Петрову / Т. Я. Николаева // Якутский медицинский журнал. – 2011. – N 3 (35). – С. 81-82.
Ответственность: Костенко Ольга Ивановна (Составитель), Николаева Татьяна Яковлевна (Прочие), Попова Татьяна Егоровна (Прочие)
Издательство: ИП Боголепов А. А.
Год выпуска: 2008
Количество страниц: 28 с.
Вторичная профилактика инсульта : методическое письмо / Министерство здравоохранения Республики Саха (Якутия) [и др.] ; составитель О. И. Костенко. - Якутск: ИП Боголепов А. А., 2008. - 24 с.