Ученая степень, ученое звание: канд. мед. наук
Количество страниц: 6 с.
A study was carried out to determine the dynamics of collagenase levels of the second subfamily (MMR-2, MMR-9) and their inhibitors (TIMP-1 and TIMP-2) in blood of patients with local cold injury (LCI). It was found out that in patients with LCI the level of MMR-2 and MMR-9 in serum increases with respect to the control group in the early period of cryodamage, and also the indices of the studied markers increase directly proportional to the volume of the affected tissues. The same dynamics was observed in the study of matrix metalloproteinase inhibitors parameters. On the basis of the obtained data and analysis of the linear regression equation a prognostic model was formed, which allows to suspect with high accuracy the level of tissue affection in the early terms of local cold injury
Значение матриксных металлопротеиназ их ингибиторов в течении раневого процесса при местной холодовой травме / М. И. Михайличенко, К. Г. Шаповалов, В. А. Мудров, О. С. Груздева // Якутский медицинский журнал. — 2020. — N 2 (70). — С. 72-76. – DOI: 10.25789/YMJ.2020.70.22.