Количество страниц: 8 с.
Случай вспышки туберкулеза с множественной лекарственной устойчивостью среди студентов Верхневилюйского техникума / Е. Ф. Лугинова, Н. Ю. Петухова, Е. М. Немытышева [и другие] // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 50-56.
Количество страниц: 4 с.
Корнилов, А. А. Организация работы в г. Якутске по больным туберкулезом, освободившимся из учреждений УФСИН / А. А. Корнилов, А. М. Лукина // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 44-46.
Количество страниц: 2 с.
We assessed the quality of BCG-M vaccine administration, using an evidence from M.N. Terekhova Kobyaysky Central District Hospital Maternity Clinic over the study period from 2011 to 2015. Qualitative assessment of scarification after administration of BCG-M vaccine was based on measuring the size of post-vaccination scar. It was concluded, that quality of vaccine administration has improved by 4.3% over the study period, but remains modest
Егорова, Р. И. Анализ показателей качества вакцинации БЦЖ в Кобяйском районе Якутии / Р. И. Егорова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 41-42.
Количество страниц: 4 с.
New Russian antitubercular agent perchlozone® was implemented to Russian practical healthcare in 2013. In the Phthisiatry Research-Practice Center, perchlozone has been used since 2016, in patients treated at the specialized department for multidrug-resistant tuberculosis (MDR TB). The article presents short results of the use of perchlozone in multimodal treatment for MDR TB: use of perchlozone allowed better treatment effectiveness in tuberculosis, although not much improvement in treatment effectiveness was observed in chronic tuberculosis; side effects developed most often in gastrointestinal tract
Догорова, О. Е. Эффективность применения противотуберкулезного препарата перхлозон в лечении туберкулеза легких с множественной лекарственной устойчивостью возбудителя / О. Е. Догорова, М. К. Винокурова, Н. Ю. Петухова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 39-41.
Количество страниц: 4 с.
Treatment results in children and adolescents with multidrug-resistant tuberculosis were analyzed. In terms of sputum conversion, more than half of (73.1%) of successfully treated cases were observed in patients who received less than 90 doses during intensive chemotherapy phase. Closure of necrotic cavities in these patients was achieved with the use of surgical treatment methods (94.4%)
Гурьева, О. И. Химиотерапия туберкулеза с множественной лекарственной устойчивостью возбудителя у детей и подростков / О. И. Гурьева, Н. А. Золотарева, С. К. Андреева // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 37-39.
Количество страниц: 2 с.
The importance of the problem of preventing and treating tuberculosis in children living in a region with worrying epidemiological situation for tuberculosis has been emphasized. With the study of socio-medical risk factors, new and better approaches to conducting preventive treatment in pediatric population should be enabled. Prediction of outcomes of preventive chemotherapy should lead to better success rates for preventive measures and reduce the risk of development of localized forms of primary tuberculosis
Гуляева, Н. А. Особенности течения первичного туберкулеза у детей в зависимости от эпидемиологической ситуации в регионе / Н. А. Гуляева, М. К. Винокурова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 36-37.
Количество страниц: 4 с.
Since 2009, Churapchinsky antituberculosis dispensary has been working without inpatient beds. Patients treated on ambulatory basis receive everything necessary at medical posts arranged to deliver directly supervised treatment. Patients who need hospitalization are treated at the Phthisiatry Research-Practice Center in Yakutsk. Over the 7-year period of work without inpatient beds, meaningful improvement in epidemiological situation was observed: key epidemiological indicators decreased by a factor of 1.7-2.2, including the incidence of multidrug-resistant tuberculosis. In large part, this was due to cooperative interagency work, when rural agencies involved in healthcare, sanitation, epidemiology, education, law enforcement, and active community members cooperate at district (or nasleg) administration level. Healthcare workers of Churapchinsky antituberculosis dispensary conduct educational population outreach work on a regular basis, and provide coordination, guidance, and instruction to primary healthcare network of the district. Churapchinsky antituberculosis dispensary is actively interacting with the head facility for tuberculosis, Phthisiatry Research-Practice Center, on the issues related to hospitalization, surgical treatment, and curator advice
Гулька, И. И. Работа Чурапчинского ПТД в условиях без стационара / И. И. Гулька, С. Д. Белолюбская // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 33-35.
Количество страниц: 6 с.
Presented in the article, are activities that the Phthisiatry Research-Practice Center undertook, with support from the Northern Forum, to address the problem of tuberculosis in circumpolar territories. Dedication of the managerial staff, along with focused efforts to make visible the problem of tuberculosis in extreme Arctic and northern circumstances, allowed the Phthisiatry Center earn its place in a number of international and Russian projects, and membership in the working groups of ICS-TB (International Circumpolar Surveillance for Tuberculosis) and Northern Forum. Collaborative projects are intended to thoroughly study the specifics of northern regions, characterize common trends, outline ways to begin to solve problems, expand and contribute to world science the knowledge about circumpolar areas, increase awareness about epidemiological situation in other regions with similar climate, geographic conditions, and common spatial, social, and economic challenges
Винокурова, М. К. Участие НПЦ "Фтизиатрия" в проектах ICS-ТВ и Северного форума по мониторингу инфекционных заболеваний / М. К. Винокурова, А. Ф. Кравченко // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 29-33.
Количество страниц: 6 с.
Over the period from 2011 to 2016, an increase in proportion of multidrug-resistant cases among pulmonary tuberculosis patients with positive microscopy and/or culture (MTB+) has been observed in Ust-Aldansky district of the Sakha Republic (Yakutia). Proportion of multidrug-resistant (MDR) cases among newly identified patients increased by a factor of 1.2 (from 27.3% to 33.3%), but remained below the all-republic level (34.6%). It should be bared in mind, that in most (68.4%) patients with MDR, resistance is, as a rule, to 3-5 or more antitubercular agents. Effective outcomes in patients, who were started on chemotherapy regimen IV during the period from 2011 to 2014, were observed in 64%, while 4% had treatment failure. We observed high rates of treatment interruptions (12%), mortality from tuberculosis (12%), and proportions of cases transferred out to Directorate of Penitentiary Service (8%), which was attributed to the majority of patients with MDR belonging to socially marginalized population groups (65.8%) often associated with treatment non-compliance and defaulting from regular medical check-ups. Successful treatment outcome in patients with MDR largely depends on well-orchestrated work of all relevant agencies, and primarily, must be supported by heads of local administrations and active members of communities in each of the districts, ‘naslegs', or settlements. All these efforts should be aimed at making sure to hospitalize these categories of patients for motivated long-term treatment
Бурнашев, И. П.Характеристика и исходы лечения больных туберкулезом с множественной лекарственной устойчивостью в Усть-Алданском районе Якутии / И. П. Бурнашев, Л. П. Яковлева // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 18-22.
Количество страниц: 4 с.
Presented are trends over time (2012-2016) in key epidemiological indicators for tuberculosis in Megino-Kangalassky district of the Sakha Republic (Yakutia), a region with high risk of tuberculosis transmission. Negative trend to increase in multidrug-resistant tuberculosis has been observed. Nevertheless, by conducting a scope of multifaceted measures, we were able to meaningfully improve treatment effectiveness in new cases, and effectiveness of regular medical check-up of existing pool of tuberculosis patients
Борисова, Е. С. Эпидемиологическая ситуация по туберкулезу и показатели туберкулеза множественной лекарственной устойчивостью в Мегино-Кангаласском районе Якутии / Е. С. Борисова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 12-14.