Место работы автора, адрес/электронная почта: Республиканская больница N 1 Национальный центр медицины ; 677019, г. Якутск, Сергеляхское шоссе, 4 ; https://rb1ncm.ru
Ученая степень, ученое звание: канд. мед. наук
Область научных интересов: Медицина,кардиология, хирургия
Деятельность: В 1993-1995 гг. - клиническая ординатура по специальности "Сердечно-сосудистая хирургия" в Медицинском институте г. Новосибирска. С 2000 г. работает в Республиканской больнице N 1 Национальном центре медицины.
Количество страниц: 9 с.
In order to assess the safety and efficacy of intraoperative local thrombolysis followed by reconstructionand plasty of the vessel, we studied the immediate results of treatment of 28 patients with thrombotic occlusionsof shunts and arteries of the lower extremities. Recently, the inflammatory theory of atherosclerosis has attractedmuch attention. The inflammatory process in atherosclerosis is observed from the early development of lesions inthe vessel wall to the destabilization and destruction of atherosclerotic plaques. The thinning of the fibrous plugand the expansion of the lipid core in it are considered important factors of destabilization leading to damage toatherosclerosis and thrombotic occlusion. The causes leading to the development of inflammatory processes inatherosclerosis are currently studied extensively, but not exhaustively. The indication for thrombolytic therapy wassevere ischemia of the lower extremities with a thrombosis duration of 3 days to 3 months and minor symptomsin the distal arterial bed. Local thrombolysis was performed using Urokinase Medak and Fortelizin, restoration ofblood flow was achieved in 25 patients. Early recurrent arterial thrombosis at the site of reconstruction developedin three patients. In the long term, the operated limb was amputated in two patients. The study showed that local intraoperative thrombolysis together with arterial reconstruction is a fairly safeand effective method for the treatment of thrombotic occlusions of the arteries of the lower extremities, shunts andprostheses at different stages of thrombus formation. This method may be a good option when selective catheter-guided thrombolysis is in doubt due to inadequate distal blood flow on angiography.
Случай использования интраоперационного локального тромболизиса в хирургическом лечении критической ишемии конечностей / А. П. Слепцов, А. П. Семенов, П. И. Захаров [и др.] ; ГАУ РС(Я) Республиканская больница N 1 Национальный центр медицины им. М. Е. Николаева, Северо-Восточный федеральный университет им. М. К. Аммосова, Медицинский институт // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: История. Политология. Право. - 2023. - N 4 (33). - C. 55-63. - DOI: 10.25587/SVFU.2023.68.92.006
DOI: 10.25587/SVFU.2023.68.92.006