Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Гигиена. Санитария,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Анатомия. Физиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Анатомия. Физиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Гигиена. Санитария.
The limits and correlation of apoptosis and necrosis of neutrophil granulocytes in venous peripheral blood in apparently healthy people were studied. It was found that w contehen increasing the content of necrotic neutrophils AnV+/PI+, the concentration of apoptotic cells AnV+/PI-increases statistically to a large extent associated with the reduction of circulating neutrophils, monocytes, and t-helper cells. Thus, activation of neutrophil loss by necrosis can become a pathogenetic mechanism of cell membrane damage (nuclear, lysosomal, or cellular), as well as the formation of T-helper immunodeficiency
Соотношение уровня некроза и апоптоза нейтрофилов периферической крови у практически здоровых северян / О. А. Ставинская, Л. К. Добродеева, С. Н. Балашова, В. П. Патракеева // Якутский медицинский журнал. — 2020. — N 4 (72). — С. 23-27
DOI: 10.25789/YMJ.2020.72.06
Количество страниц: 4 с.
The significance of polymorphic variants of amino oxidase AOC1 and histamine-N-methyltransferase HNMT genes, involved in histamine metabolism, with predicting the risk of developing bronchial asthma (BA) in children living in the Republic of Bashkortostan was evaluated. Associations of the rs1049793 * CC genotype and the rs1049793 * C allele of the AOC1 gene with the development of ВА were revealed with significant reductions in spirography indices in children of Russian ethnicity. There were associations of the rs1801105 * CT genotype and the rs1801105 * T allele of the HNMT gene with a significant decrease in MEF25 in BA patients of Tatar ethnicity. The results of this study indicate the role of polymorphic variants of the AOC1 and HNMT genes in the development of BA
Анализ ассоциаций полиморфных вариантов генов аминоксидазы 1 АОС1 и гистамин-N- метилтранферазы HNM с развитием бронхиальной астмы у детей / О. Н. Савельева, А. С. Карунас, Ю. Ю. Федорова [и другие] // Якутский медицинский журнал. — 2020. — N 4 (72). — С. 20-22
DOI: 10.25789/YMJ.2020.72.05
Количество страниц: 4 с.
- Математика. Естественные науки > Общая биология. Антропология. Вирусология. Микробиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Общая биология. Антропология. Вирусология. Микробиология.
The article presents the study of the characteristics of the membrane potential of mitochondria (MPM) granulocytes in 72 children with congenital lung malformations (CLM). There was a 5-fold increase in the proportion of cells with reduced granulocyte MPM(ΔΨm) compared to the control group. During the periods of exacerbation of the disease, the number of granulocytes with reduced potential increased by 8 times accompanied by the growth of luminol-and lucigenin-dependent chemiluminescence of whole blood phagocytes with spontaneous, significant decrease in the I-lum and I-luc stimulation indices by 30 and 25%. Negative dynamics of the stimulation index indicates the depletion of reserve capacities of the phagocytic system in children of the study group. There are statistically significant direct correlations between the level of granulocytes with reduced MPM(ΔΨm) and indicators of phagocytic activity of leukocytes
Оценка мембранного потенциала митохондрий гранулоцитов у детей с хроническими воспалительными заболеваниями легких / Г. П. Евсеева, О. А. Лебедько, С. В. Супрун [и другие] // Якутский медицинский журнал. — 2020. — N 4 (72). — С. 10-13
DOI: 10.25789/YMJ.2020.72.02
Количество страниц: 4 с.
The analysis of the clinical and endoscopic picture of peptic ulcer disease (UD) in patients in the studied ethnic groups in the Far North conditions was carried out. Duodenal ulcer was detected in both ethnic groups, more often in men. In the indigenous population UD was detected mainly in the middle working age, more often with the localization of an ulcer in the stomach. In patients with a long ulcer history, the degree of HP contamination in the mucous membrane is reduced. At the same time, weak contamination is more frequent in the group of patients from the indigenous population than in non-indigenous one
Отличительные особенности язвенной болезни желудка и двенадцатиперстной кишки в условиях Крайнего Севера / Н. В. Аввакумова, Л. Г. Чибыева, Н. Н. Васильев, Л. В. Дайбанырова // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 84-87
DOI: 10.25789/YMJ.2020.69.20
Количество страниц: 4 с.
The article presents the key indicators of the maternal and child health service for 2000-2018 in the Arctic regions of the Republic Sakha (Yakutia) and in general in the RS (Ya) and the Russian Federation. The article analyzes the indicator of infant and maternal mortality in the RS (Ya), including in the Arctic zone. It is noted that according to the official medical statistics, the infant and maternal mortality rate in the Arctic zone of the Republic Sakha (Yakutia) has reached a historical minimum
Основные индикаторы эффективности государственных программ охраны материнства и детства в Арктической зоне Республики Саха (Якутия) / Т. Е. Бурцева, Н. И. Дуглас, С. С. Слепцова [и другие] // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 77-80
DOI: 10.25789/YMJ.2020.69.18
Количество страниц: 4 с.
Article is intended to acquaint the reader with experience in applying the methods of the human and natural sciences for the reconstruction of the diet of the ancient Yakuts. Ethnographic texts, archaeological material, analysis of the stable carbon isotopes δ13С and nitrogen δ15N on the bone collagen of humans, animals and fish were used. The advantages and disadvantages of using this analysis are noted. Detection of toxic substances in the hair of the deceased was made
Междисциплинарный подход в изучении питания якутов с XVII по XIX в. / Л. Г. Романова, Н. В. Покатилова, В. Бальтер, Э. Крюбези // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 73-76
DOI: 10.25789/YMJ.2020.69.17
Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Анатомия. Физиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Психиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Анатомия. Физиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Психиатрия.
The authors analyzed dietary intake of freestyle wrestlers depending on the season, taking into account the daily energy expenditure. The obtained data conclude that the daily food ration calorie does not reimburse the daily energy consumption of athletes. The chemical composition of nutrients in the daily diet of athletes quantitatively and qualitatively does not correspond to the standards recommended for freestyle wrestlers
Анализ фактического питания спортсменов-единоборцев в условиях Якутии / Л. И. Константинова, Е. И. Семёнова, А. В. Ефремова [и другие] // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 68-73
DOI: 10.25789/YMJ.2020.69.16
Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Анатомия. Физиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Анатомия. Физиология.
The results of comparative study of chronic generalized periodontitis (CGP) of average severity in elderly and senile patients are reported. The development of CGP of medium severity in elderly and senile people is accompanied by activation of humoral immunity with excessive synthesis of all immunoglobulins in blood and saliva, the pressure of complementary activity is established, analysis of indicators of general and local immunity indicates differences between elderly and se-nile patients
Показатели врожденного и адаптивного иммунитета при хроническом генерализованном пародонтите у больных пожилого и старческого возраста / И. С. Пинелис, Ю. И. Пинелис, М. С. Малежик, И. Д. Ушницкий // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 63-68
DOI: 10.25789/YMJ.2020.69.15
Количество страниц: 6 с.
The article analyzes the respiratory function indicators in two ethnically different groups (Yakuts and Russians) of the Republic Sakha (Yakutia) of the same age and sex. It shows that in the Yakuts, compared to Russians, some reserve respiratory system indicators are reduced. The results of a study of respiratory function in smokers show a significant respiratory obstruction caused by tobacco smoke. The degree of respiratory obstruction in smokers increases in direct proportion to the length of time they smoke. Against the background of smoking increases hypoxia, blood oxygenation and oxygen transport to tissues. In smokers, the rate of lipid peroxidation and the condition of antioxidant protection of the body depend on the length of time they smoke
Физиолого-биохимические аспекты табакокурения в условиях Якутии / Г. Е. Миронова, Л. Д. Олесова, Е. И.Семенова [и другие] // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 58-62
DOI: 10.25789/YMJ.2020.69.14
Количество страниц: 4 с.
The article presents the medical and demographic situation in the Republic Sakha (Yakutia) for the period 2010-2017. The authors evaluated medical and demographic indicators based on official data of the Federal State Statistics Service of the Russian Federation (FSSS or Rosstat) and the Territorial body of the FSSS for the Republic Sakha (Yakutia). An attempt was made to predict the possibility of fulfilling indicator values in accordance with the strategic objectives of the development of the Russian Federation until 2024. The authors came to the conclusion that the goals would be achievable, but in case that the rates of reduction of total mortality and infant mortality, as well as an increase in life expectancy in RS (Yakutia) will be maintained and even improved
Медико-демографическая ситуация в Республике Саха (Якутия) в контексте стратегических задач развития Российской Федерации до 2024 г. / Л. Ф. Тимофеев, Н. В. Саввина, В. Г. Кривошапкин [и другие] // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 49-52
DOI: 10.25789/YMJ.2020.69.12