Количество страниц: 4 с.
The article presents the results of the fisrt molecular genetic study in the EXT1 and EXT2 genes among patients with hereditary multiple exostoses (HME) ant their relatives. A rare nonsense mutation c.751С>T (p.Gln251*) in exon 5 of ЕХТ2 gene in a heterozygous state was detected. That was the cause of HME among patients of the Yakut ethnic group. At present we are conducting the investigation to search mutations in ЕХТ1 and ЕХТ2 genes in other families with HME
Поиск мутаций в генах EXT1 и EXT2 у больных с множественной экзостозной хондродисплазией в Республике Саха (Якутия) / А. Е. Яковлева, А. Л. Данилова, Д. А. Петухова [и другие] // Якутский медицинский журнал. — 2020. — N 4 (72). — С. 31-33
DOI: 10.25789/YMJ.2020.72.08
Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Анатомия. Физиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Анатомия. Физиология.
The results of comparative study of chronic generalized periodontitis (CGP) of average severity in elderly and senile patients are reported. The development of CGP of medium severity in elderly and senile people is accompanied by activation of humoral immunity with excessive synthesis of all immunoglobulins in blood and saliva, the pressure of complementary activity is established, analysis of indicators of general and local immunity indicates differences between elderly and se-nile patients
Показатели врожденного и адаптивного иммунитета при хроническом генерализованном пародонтите у больных пожилого и старческого возраста / И. С. Пинелис, Ю. И. Пинелис, М. С. Малежик, И. Д. Ушницкий // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 63-68
DOI: 10.25789/YMJ.2020.69.15
Количество страниц: 8 с.
Показатели заболеваемости дифиллоботриозом населения Республики Саха (Якутия) / Е. В. Пшенникова, Я. А. Ахременко, И. В. Николаева, З. А. Захарова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2020. — N 1 (18). — С. 75-81. — DOI: 10.25587/SVFU.2020.18.61535
DOI: 10.25587/SVFU.2020.18.61535
Количество страниц: 4 с.
Показатели и причины смертности детского населения Арктических районов Республики Саха (Якутия) / С. А. Евсеева, Т. Е. Бурцева, А. Г. Егорова, А. М. Макарова, М. С. Саввина, М. П. Слободчикова // Якутский медицинский журнал. — 2020. — N 2 (70). — С. 69-72. – DOI: 10.25789/YMJ.2020.70.21.
DOI: 10.25789/YMJ.2020.70.21
Количество страниц: 2 с.
Мордовская, Л. И. Показатели иммунологического статуса детей и подростков, больных туберкулезом с лекарственной устойчивостью возбудителя / Л. И. Мордовская, О. И. Гурьева, Е. А. Алексеева // Туберкулез болезни и легких. — 2013. — Т. 90. — N 6. — С. 56.
Количество страниц: 4 с.
The day patient department is a medical-diagnostic department of the polyclinic, which has become common nowadays and has a number of economic and psychological advantages in comparison with the traditional hospital. There are 17 day patient departments in Yakutsk City. In order to study the indicators of the day patient department in Polyclinic1 of Yakutsk City, a retrospective analysis of case histories of 76 patients, 36 men and 40 women, an average age of 52 years, was conducted. The analysis revealed most common diseases in men and women coming to the day patient department. Women had musculoskeletal system diseases (52 %), while men had circulatory system diseases (35 %) and digestive organs (47 %). The average length of stay of the patient on a daily bed in the clinic was 10-12 days. The patients had a comorbid condition, the presence of 2 to 4 diseases, which always adversely affected the patient’s condition. Modern methods of diagnosis and treatment in the day patient department allows reducing the number of hospitalizations in the in-patientdepartment and provides an opportunity to receive full-fledged treatment of diseases without interruption of work
Бессонова, Н. Г. Показатели лечебной работы дневного стационара ГБУ РС(Я) "Поликлиника N 1 г. Якутска" / Н. Г. Бессонова, П. П. Бессонов // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2017. — N 4 (09). — С. 23-26.
Количество страниц: 4 с.
Changes in lipid metabolism, depending on the length of residence in the North, in the winter season in the non-indigenous population of Yakutia, aged 18 to 62 years, were examined. It was revealed that the adaptation of the organism to the North conditions is accompanied by changes in lipid metabolism. In the first year of residence in the North in the blood serum high cholesterol is compensated by increasing the content of HDL cholesterol and APO A-I. This is indicated by the coefficient of atherogenicity, which varies within the limits of normal values. At residence in the North from 2 to 5 years lipid metabolism indicators correspond to normal values; after 5 years – there is an increase in the level of cholesterol and atherogenicity coefficient due to an increase in LDL cholesterol.
Показатели липидного обмена у пришлых жителей Якутии в зависимости от сроков проживания на Севере / З. Н. Кривошапкина, Г. Е. Миронова, Е. И. Семенова, Л. Д. Олесова, А. И. Яковлева // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 28-30.
DOI: 10.25789/YMJ.2018.62.09
Количество страниц: 4 с.
Rates of multidrug-resistance (MDR), including extensive drug-resistance (XDR), were analyzed in new cases of pulmonary tuberculosis (TB) with positive microscopy and/or culture tests, for the Sakha Republic (Yakutia), Yakutsk, rural districts, and for 5 geographical zones composing the territory of Yakutia, over the period from 2012 to 2017. During the study period, we observed unfavorable trend to increasing proportion of pulmonary tuberculosis patients with primary MDR in Yakutia (from 23% to 32.8%). The same rates for Yakutsk and rural districts increased by factors of 1.6 (from 22.5 to 36.7%) and 1.2 (from 23.6 to 29.2%), respectively. In the Arctic zone of Yakutia, for the last 5 years, a decrease was observed (by a factor 1.5) in proportion of MDR TB in new patients with pulmonary TB. In the Eastern Yakutia zone, over the period 2016 to 2017, no case with primary MDR was detected. In the rest 3 geographical zones, the named proportion was observed to increase. In 2012, a solitary case of XDR in a new patient was registered in Yakutia. During the study period, proportion of XDR in new patients with pulmonary TB showed trend to increase
Яковлева, Л. П. Показатели множественной лекарственной устойчивости среди впервые выявленных больных туберкулезом в Республике Саха (Якутия) / Л. П. Яковлева, О. Д. Кондратьева, А. У. Бурнашева // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 121-124.
Количество страниц: 3 с.
We performed macromorphometry using the Body Logic system of mammary glands of healthy women and women with a confirmed diagnosis of breast cancer, anthropometry and somatotyping with the release of normosthenic, asthenic and picnic types of physique. It was revealed that women of a picnic somatotype are more predisposed to the development of tubular deformation of the mammary glands in comparison with women of other body types. In the physique of women with breast cancer asthenomorphy predominates.
Показатели морфометрии молочных желез женщин разных соматотипов в норме и при раке молочной железы / Р. А. Пахомова, Г. Э. Карапетян, Л. В. Кочетова, Л. В. Синдеева, Н. А. Ратушный, А. В. Зюзюкина // Якутский медицинский журнал. — 2019. — N 4 (68). — С. 126-128. — DOI: 10.25789/YMJ.2019.68.36
DOI: 10.25789/YMJ.2019.68.36
Количество страниц: 4 с.
Lipid peroxidation of native people and non-native residents in Yakutia was compared. The obtained data clearly indicate existence of lengthening of the adaptation phase under modern socio-economic conditions of life of the population of Yakutia compared to similar studies of the several decades before. It is likely that adaptation to the harsh conditions of the North is associated with the activation of an antioxidant-responsive element that induces the expression of proteins responsible for maintaining internal homeostasis.
Показатели перекисного окисления липидов в организме приезжих жителей Якутии / В. М. Николаев, С. И. Софронова, Л. Д. Олесова, С. Д. Ефремова, А. С. Гольдерова, Ф. В. Винокурова, Е. Д. Охлопкова, Л. И. Константинова, А. И. Яковлева, А. В. Ефремова, Е. К. Румянцев, К. М. Степанов, А. А. Григорьева, Н. К. Чирикова, А. С. Попова, С. А. Федорова // Якутский медицинский журнал. — 2019. — N 4 (68). — С. 60-63. — DOI: 10.25789/YMJ.2019.68.16.
DOI: 10.25789/YMJ.2019.68.16