Количество страниц: 4 с.
Корнилов, А. А. Организация работы в г. Якутске по больным туберкулезом, освободившимся из учреждений УФСИН / А. А. Корнилов, А. М. Лукина // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 44-46.
Количество страниц: 4 с.
Based on retrospective analysis of outcomes of multimodal treatment of new cases of multidrug-resistant tuberculosis in Yakutsk over the period from 2012 to 2014, crucial role of surgical intervention is shown in cases of chemotherapy failure. Criteria for successful surgical treatment included: sputum conversion, necrotic cavity closure, transfer of a patient to category III for regular medical check-up. Analysis of long-term outcomes of treatment with the use of surgical methods showed a good clinical effectiveness rate (82.2%)
Кондаков, С. Н. Роль хирургических методов в комплексном лечении впервые выявленных больных с множественной лекарственной устойчивостью в г. Якутске / С. Н. Кондаков, Ю. С. Иванов // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 42-44.
Количество страниц: 2 с.
We assessed the quality of BCG-M vaccine administration, using an evidence from M.N. Terekhova Kobyaysky Central District Hospital Maternity Clinic over the study period from 2011 to 2015. Qualitative assessment of scarification after administration of BCG-M vaccine was based on measuring the size of post-vaccination scar. It was concluded, that quality of vaccine administration has improved by 4.3% over the study period, but remains modest
Егорова, Р. И. Анализ показателей качества вакцинации БЦЖ в Кобяйском районе Якутии / Р. И. Егорова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 41-42.
Количество страниц: 4 с.
New Russian antitubercular agent perchlozone® was implemented to Russian practical healthcare in 2013. In the Phthisiatry Research-Practice Center, perchlozone has been used since 2016, in patients treated at the specialized department for multidrug-resistant tuberculosis (MDR TB). The article presents short results of the use of perchlozone in multimodal treatment for MDR TB: use of perchlozone allowed better treatment effectiveness in tuberculosis, although not much improvement in treatment effectiveness was observed in chronic tuberculosis; side effects developed most often in gastrointestinal tract
Догорова, О. Е. Эффективность применения противотуберкулезного препарата перхлозон в лечении туберкулеза легких с множественной лекарственной устойчивостью возбудителя / О. Е. Догорова, М. К. Винокурова, Н. Ю. Петухова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 39-41.
Количество страниц: 4 с.
Treatment results in children and adolescents with multidrug-resistant tuberculosis were analyzed. In terms of sputum conversion, more than half of (73.1%) of successfully treated cases were observed in patients who received less than 90 doses during intensive chemotherapy phase. Closure of necrotic cavities in these patients was achieved with the use of surgical treatment methods (94.4%)
Гурьева, О. И. Химиотерапия туберкулеза с множественной лекарственной устойчивостью возбудителя у детей и подростков / О. И. Гурьева, Н. А. Золотарева, С. К. Андреева // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 37-39.
Количество страниц: 2 с.
The importance of the problem of preventing and treating tuberculosis in children living in a region with worrying epidemiological situation for tuberculosis has been emphasized. With the study of socio-medical risk factors, new and better approaches to conducting preventive treatment in pediatric population should be enabled. Prediction of outcomes of preventive chemotherapy should lead to better success rates for preventive measures and reduce the risk of development of localized forms of primary tuberculosis
Гуляева, Н. А. Особенности течения первичного туберкулеза у детей в зависимости от эпидемиологической ситуации в регионе / Н. А. Гуляева, М. К. Винокурова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 36-37.
Количество страниц: 4 с.
Since 2009, Churapchinsky antituberculosis dispensary has been working without inpatient beds. Patients treated on ambulatory basis receive everything necessary at medical posts arranged to deliver directly supervised treatment. Patients who need hospitalization are treated at the Phthisiatry Research-Practice Center in Yakutsk. Over the 7-year period of work without inpatient beds, meaningful improvement in epidemiological situation was observed: key epidemiological indicators decreased by a factor of 1.7-2.2, including the incidence of multidrug-resistant tuberculosis. In large part, this was due to cooperative interagency work, when rural agencies involved in healthcare, sanitation, epidemiology, education, law enforcement, and active community members cooperate at district (or nasleg) administration level. Healthcare workers of Churapchinsky antituberculosis dispensary conduct educational population outreach work on a regular basis, and provide coordination, guidance, and instruction to primary healthcare network of the district. Churapchinsky antituberculosis dispensary is actively interacting with the head facility for tuberculosis, Phthisiatry Research-Practice Center, on the issues related to hospitalization, surgical treatment, and curator advice
Гулька, И. И. Работа Чурапчинского ПТД в условиях без стационара / И. И. Гулька, С. Д. Белолюбская // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 33-35.
Количество страниц: 6 с.
Presented in the article, are activities that the Phthisiatry Research-Practice Center undertook, with support from the Northern Forum, to address the problem of tuberculosis in circumpolar territories. Dedication of the managerial staff, along with focused efforts to make visible the problem of tuberculosis in extreme Arctic and northern circumstances, allowed the Phthisiatry Center earn its place in a number of international and Russian projects, and membership in the working groups of ICS-TB (International Circumpolar Surveillance for Tuberculosis) and Northern Forum. Collaborative projects are intended to thoroughly study the specifics of northern regions, characterize common trends, outline ways to begin to solve problems, expand and contribute to world science the knowledge about circumpolar areas, increase awareness about epidemiological situation in other regions with similar climate, geographic conditions, and common spatial, social, and economic challenges
Винокурова, М. К. Участие НПЦ "Фтизиатрия" в проектах ICS-ТВ и Северного форума по мониторингу инфекционных заболеваний / М. К. Винокурова, А. Ф. Кравченко // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 29-33.
Количество страниц: 4 с.
Presented is a comparative analysis of various techniques to perform reamputation of the main bronchus stump, in 30 patients, who had bronchial fistulas with various localizations and pleural empyema with various severity. High success rate of surgical treatment (90%) was observed in patients treated via pleural space approach during the first three days after bronchial fistula developed, and in the absence of visible manifestations of empyema development. Treatment effectiveness was fairly high (95%) in patients, who had leakage in the left main bronchus stump and signs suggesting presence of chronic empyema, and who were treated using collateral technique of stump amputation. In patients with leakage in right main bronchus stump and chronic empyema, with surgery performed via transsternal-transpericardial approach, treatment effectiveness was 70%. Development of rational tactic for using various surgery techniques to treat main bronchus stumps depending on severity of pleural empyema helped avoid troublesome complications after surgery and achieve the best possible treatment success rate
Винокуров, И. И. Сравнительный анализ различных методов повторной ампутации культи главного бронха / И. И. Винокуров, А. Ф. Кравченко // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 27-29.
Количество страниц: 6 с.
2000 WHO guidelines for treatment of multidrug-resistant tuberculosis recommend chemotherapy duration of 18 to 24 months, while neglecting the use of surgical treatment. In particular, the guidelines contained no optimal time to surgery or surgical interventions for patients with irreversible destructive alterations. We used patterns of morphogenesis in multidrug-resistant tuberculosis to develop an algorithm to organize and manage the surgical treatment of patients. Based on algorithm, patients are distributed depending on their disease course patterns: extensive destructive disease or limited forms of tuberculosis. For patients with extensive destructive tuberculosis, an optimal time for surgery is between months 4-6 during intensive phase, when tuberculosis has proliferative disease course. In patients who have limited localized disease, surgery is optimal between months 3-4 since the start of chemotherapy (90-120 doses). Analysis of surgical treatment results in patients with multidrug-resistant tuberculosis showed high effectiveness of multimodal treatment in 93.1% of patients with extensive disease (exacerbation was observed in 6.9%), and in 97.6% of patients with localized multidrug-resistant tuberculosis (with exacerbation in 2.4%)
Винокуров, И. И. Особенности организации хирургического лечения больных с множественной лекарственной устойчивостью туберкулеза легких в условиях региона Крайнего Севера / И. И. Винокуров, А. Ф. Кравченко // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 22-27.