Количество страниц: 6 с.
A vacA gene is important virulence factor that encodes vacuolating toxin and presents in all strains of Helicobacter pylori. There is significant difference between strains in vacuolating activity determined by different sequences in the middle (m) and signal (s) regions. Helicobacter pylori vacAm has m1 and m2 alleles, vacAs has s1 and s2 alleles. The higher grade of cytotoxic activity shows Helicobacter pylori with vacAs1m1 strains than s1m2, while s2m2 has not produced vacuolating cytotoxin. The effect of vacA gene alleles on gastroduodenal diseases in patients of Yakutia earlier has not been studied. The aim of this work is an associative analysis of the clinical outcomes of the vacA Helicobacter pylori variant gene and its association with the course of gastroduodenal diseases among Yakuts. According to the results of the histological report, 154 patients (out of 322 examined) were included in the study, who had H. pylori in the antrum of the stomach. Patients were divided into two groups: chronic gastritis (n=65) and chronic gastritis with erosive and ulcerative lesions (n=89). The average age was 26,6 years. The diagnosis of chronic gastritis was established in 65 cases (42,2%), and chronic gastritis with erosive and ulcerative lesions was diagnosed in 89 cases (57,7%). A vacAs1m1 was found in 30 out of 39 patients with erosive and ulcerative lesions (76,9%) (p
Анализ клинических исходов у пациентов с гастродуоденальными заболеваниями в зависимости от вариантов гена vacA Helicobacter pylori в Якутии / Н. Н. Готовцев, Н. А. Барашков, Т. В. Борисова [и другие] // Якутский медицинский журнал. — 2020. — N 4 (72). — С. 69-73
DOI: 10.25789/YMJ.2020.72.18
Количество страниц: 4 с.
In this paper we presented the results of the study of clinical outcomes in patients with gastroduodenal diseases in Yakutia depending on the presence of the cytotoxin-associated gene A (cagA) in Helicobacter pylori genome. The relationship between cagA+ strains and more severe clinical outcomes (erosion and ulcers) in patients with gastroduodenal diseases associated with Helicobacter pylori in Yakutia has been shown.
Анализ клинического течения гастродуоденальных заболеваний в Якутии в зависимости от наличия цитотоксин-ассоциированного гена А (cagA) в геноме Helicobacter pylori / Н. Н. Готовцев, Н. А. Барашков, Т. В. Борисова, М. В. Пак, М. П. Алексеева, Н. Н. Иннокентьева, К. С. Лоскутова, В. Г. Пшенникова, А. М. Рафаилов, С. Н. Леханова, С. А. Федорова // Якутский медицинский журнал. — 2018. — N 3 (63). — С. 11-14
DOI: 10.25789/YMJ.2018.63.03
Количество страниц: 6 с.
This article contains an analysis of the ACS mortality in 2020 in the Intensive Care Unit of the Regional Vascular Center No. 1, Republic’s Hospital No. 2 -Center for Emergency Medical Aid in 2020. The aim was to assess the mortality rates, the influence of concomitant diseases, age, and the coronavirus infection; to assess the impact of primary percutaneous coronary intervention (PCI) on survival in the department; and to improve the quality of medical services provided to the population. The study covered 115 patients who died in the Cardiac Intensive Care Unit. The severity of the condition at admission, concomitant diseases, and the effect of a new coronavirus infection were taken into account. Compared to 2019, the mortality rate increased by 83%. The factors that negatively affect the level of hospital mortality are as follows: cardiogenic shock, female sex, old and senile age, kidney disease, diabetes mellitus, previous myocardial infarction, hospitalization period, distance from the PCI center, and the severity of the condition upon admission. Concomitant pathologies were detected in more than 90% of the patients. The peculiarities of the course of coronavirus infection in patients with coronary artery disease have become an increase in the class of angina pectoris, an increase in the risk of acute coronary events; however, we have yet to study the effect of the new coronavirus infection and analyze the new data
Герасимов, Ф. В. Анализ летальности при остром коронарном синдроме по показателям отделения реанимации и интенсивной терапии N2 регионального сосудистого центра N1 РБ N2-ЦЭМП / Ф. В. Герасимов, Н. В. Степанова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2021. — N 1 (22). — С. 52-56.
DOI: 10.25587/SVFU.2021.22.1.007
Количество страниц: 4 с.
Each ecological region has individual characteristics of metabolism particularly because of the indefinite landscape zone that can be inhabited by people of different ethnic and racial origin. The environmental factor of nutrition has a great influence on the metabolism characteristics. What macro- and micronutrients are consumed with food becomes a prognostic sign of the development of alimentary-dependent deviations that directly affect functional parameters of the body systems. The diet of 17-21 year old male indigenous residents of Magadan region (n = 38) and Chukotka Autonomous District (n = 52) has been analyzed. All the examinees were full-time students having similar living conditions. The ASPON-Nutrition program (Russia) was used to evaluate the young subjects' nutritional profiles by analyzing their daily diets. The studied parameters were proteins, fats, carbohydrates, fiber, vitamins, and macro- and microelements. In addition, the energy value of the daily diet was assessed in kcal / day. Larger deviations from the current normative values of the body physiological needs in macro- and micronutrients have been found. The nutritional imbalance characterized by insufficient intake of proteins, fats, essential trace elements, and vitamins against the background of reduced energy value of daily calorie content has been shown. The revealed deficiency is much more typical at young men living in the city of Magadan. In general, the multilateral imbalance established in the diet of young indigenes indicates a violation of the basic principles of healthy eating (satisfying energy needs, balancing proteins, fats, carbohydrates) and can be associated with avoiding the traditional type of the diet by the indigenous population and turning to the classical Caucasian one which does not provide all the needs of the body of this ethnicity
Аверьянова, И. В. Анализ макро-и микронутриентного профиля рациона питания юношей-аборигенов Северо-Востока России / И. В. Аверьянова, С. И. Вдовенко // Якутский медицинский журнал. — 2020. — N 4 (72). — С. 102-105
DOI: 10.25789/YMJ.2020.72.25
Количество страниц: 3 с.
- Общественные науки. Образование > Экономика. Экономические науки. Политическая экономия > Экономическое положение. Экономическая политика. Управление и планирование в экономике. Производство. Услуги. Цены,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Управление предприятиями. Организация производства, торговли и транспорта,
- НАУКА ЯКУТИИ > ОБЩЕСТВЕННЫЕ НАУКИ > Экономика. Экономические науки. Политическая экономия.
Местникова, А. В. Анализ международного маркетинга компании InDrive / А. В. Местникова ; Северо-Восточный федеральный университет им. М. К. Аммосова, Финансово-экономический институт // Социально-экономические проблемы северного региона: новые глобальные вызовы 21 века : сборник трудов научно-практической конференции, посвященной 30-летию основания Финансово-экономического института СВФУ (с международным участием), г. Якутск, 12 мая 2023 г. / [редакционная коллегия: А. Т. Набережная, Р. Р. Ноговицын, Г. И. Рац и др.]. - Якутск : Издательский дом СВФУ, 2023. -1 файл (355 с. ; 10,6 Мб). - С. 49-51.
Количество страниц: 4 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Терапия,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Педиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина.
To study the microflora of the oral cavity, children and adolescents living in Yakutsk were examined. Smears from the mucous throat and tonsils were used to conduct a microbiological analysis of the oral microflora in frequently ill children, as well as in children with acute tonsillopharyngitis, acute pharyngitis, and angina, also using the express-diagnosis method Streptatest for the presence of beta-hemolytic streptococcus group A (BHSA). In the frequently ill children, yeast fungi of the genus Candida, bacteria of the genuses Staphylococcus, Streptococcus and Klebsiella were found. As a result of the treatment in children, the anaerobic index is shifted to the normal range. According to the rapid test for BHSA, a positive result was detected in 37% of patients. Timely establishment of BHSA allowed conducting eradication antibacterial therapy, which led to recovery without complications.
Анализ микрофлоры ротовой полости у детей / Н. М. Захарова, Н. А. Гуляева, А. М. Аммосова, С. В. Маркова, М. В. Ханды, С. Ю. Артамонова, Л. А. Степанова, В. Б. Егорова // Якутский медицинский журнал. — 2018. — N 3 (63). — С. 32-35
DOI: 10.25789/YMJ.2018.63.09
Количество страниц: 4 с.
Анализ микроциркуляторных нарушений у больных красным плоским лишаем слизистой полости рта / Ю. А. А. Македонова, Е. В. Фомичев, К. В. Жмеренецкий, А. В. Юркевич, И. Д. Ушницкий // Якутский медицинский журнал. – 2019. – N 1 (65). – С. 48-51. – DOI:10.25789/YMJ.2019.65.11
DOI: 10.25789/YMJ.2019.65.15
Количество страниц: 6 с.
Acute respiratory infections (ARI) is a leader in the structure of general diseases of the population. Annually, Russia has about 70 thousand ARI cases per 100 thousand of the child population. The maximum frequency of acute respiratory infections is noted in age from 6 months to 6 years; in this group, the highest incidence of acute respiratory infections is observed in preschool age children. In the causes of acute respiratory disease, viral infections take a lead (90 %) and bacterial pathogens account fot only a minor part. Despite this, almost 25-85 % of pediatricians prescribe antibiotics for their patients with acute respiratory infections. Aim. Analysis of the spectrum of antibacterial drugs used for acute respiratory infections in preschool children in the outpatient tratment. Methods. The study was formed by a representative group in the amount of 1,248 outpatient preschool children. Results.In the period 2009-2010, the structure of ARI was dominated by the incidence of acute nasopharyngitis at over 60 %. The pharmacoepidemiological analysis showed frequent use of systemic antibiotics for children with acute nasopharyngitis on the outpatient basis. It was found that the antibiotic therapy was applied in 43 % (2009) and 37 % (2010) ARI cases. Aminopenicillins, combined penicillins, macrolides, cephalosporins of the 3d generation were used most often. Conclusion.Given the prevalence of acute nasopharyngitis cases among the nosological forms of ARI, it should be noted that most of them have an uncomplicated form, which sould serve as the basis for strict adherence to the approved standards of ARI treatment in outpatient care
Акимова, Л. С. Анализ назначений системных антибиотиков при острых респираторных инфекциях детям дошкольного возраста в амбулаторных условиях / Л. С. Акимова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2017. — N 4 (09). — С. 12-16.
Количество страниц: 5 с.
Анализ накопления дефектов при эксплуатации резервуаров для хранения нефтепродуктов / А. П. Аммосов, Н. И. Голиков, Н. Н. Терентьев, З. Г. Корнилова, Г. С. Аммосов, В. Б. Стрижов // Эксплуатационная прочность сварных соединений и конструкций Севера : сборник статей доктора технических наук, профессора А. П. Аммосова, посвященный 80-летию. — Якутск : Цумори Пресс, 2017. — С. 134-138.
Количество страниц: 8 с.
The article deals with theoretical problems of national identity. Special attention is paid on scientific studies and monographs related to the real situation in Central Asia. Which they addressed issues of national identity, the impact of national independence on ethnic and social harmony in the region. The place of national culture, language and rituals in the development of national consciousness. And also, analyzed the empirical materials influencing the growth of self-consciousness that for actual implementation of these actions is important to the study of public opinion. So how the polls develop the worldview of the population and ensure an active participation in political events. However, these surveys are important in improving the political, legal, economic and other knowledge of the population and in defining political and empirical sides of the problem being studied. Furthermore, it is stated that the study of national identity on the basis of socio-theoretical methods and the political and empirical information has also practical importance, since the provision of national identity due to the strengthening of international co-operation and unity, the formation of a common social consciousness, the assertion of General civil mentality.
Назаров, Н. А. Анализ некоторых теорий национального самосознания народов Центральной Азии / Н. А. Назаров // Северо-Восточный гуманитарный вестник. — 2017. — N 3 (20). — С. 104-111.