Количество страниц: 4 с.
- Математика. Естественные науки > Общая биология. Антропология. Вирусология. Микробиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Общая биология. Антропология. Вирусология. Микробиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина.
The article presents a review of the literature about the genetic factors of predisposition to autoimmune to thyroid disorders, the main of which are diffuse toxic goiter and autoimmune thyroiditis. Studies of recent years have made it possible to establish that genetic factors make a significant contribution to the development of the autoimmune process at autoimmune thyroid disorders.
Генетические факторы предрасположенности к аутоиммунным тиреопатиям / Т. К. Сунхалырова, В. В. Додохов, Н. А. Соловьева, Н. И. Палова, Н. П. Филиппова, Л. М. Нуестроева, М. А. Варламова, А. Т. Дьяконова, Х. А. Куртанов //Якутский медицинский журнал. – 2018. – N 2 (62). – C. 106-109. — DOI: 10.25789/YMJ.2018.62.32
DOI: 10.25789/YMJ.2018.62.32
Количество страниц: 4 с.
The risk factors for COPD development among residents of Yakutsk, working in harmful working conditions, with a significant experience of smoking and respiratory complaints, were studied. A questioning and examination of the function of external respiration (spirometry) was conducted. The questionnaire developed by the FMBA RF ҺPulmonology Research Instituteһ (Moscow) contained questions on the identification of risk factors and respiratory symptoms. A SAT test was also used to assess the effect of COPD on the health of the questioned person.
Анализ выявляемости факторов риска ХОБЛ у населения г. Якутска / А. Н. Аргунова, А. Н. Хорунов, Р. Н. Яковлева // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 103-105 — DOI: 10.25789/YMJ.2018.62.31.
DOI: 10.25789/YMJ.2018.62.31
Количество страниц: 4 с.
The data of the primary disability of the adult and children population in the Republic of Sakha (Yakutia) are presented, what is more in the context of districts / uluses over a ten-year period (2007-2016). The percentile method revealed the levels of primary disability: high, above average, medium, below average and low, which for clarity were painted in appropriate colors. The analysis revealed trends in the dynamics of indicators of primary disability (PD), as well as administrative-territorial entities, where it is better or worse PD level separately among the adult and child population. In addition, the structure of the main causes of disability and distribution to disability groups is presented.
Состояние первичной инвалидности взрослого и детского населения в Республике Саха (Якутия) / Л. Ф. Тимофеев, А. И. Гоголева, В. Г. Кривошапкин, А. Л. Тимофеев // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 100-103 — DOI: 10.25789/YMJ.2018.62.30.
DOI: 10.25789/YMJ.2018.62.30
Количество страниц: 6 с.
In the present work there are modern data on epizootological epidemic monitoring of anthrax in the central and southern economic zones of the Republic of Sakha (Yakutia), which significantly clarify the quantitative and qualitative aspects of the indicated problem. Thus, the maximum number of epizootics of anthrax (numerator) and disadvantaged settlements (denominator) is registered in the areas of the central economic zone (323/109), and their respective minimum values are in the areas of the south economic zone (2/2). It has been determined the intensity of death of domestic animals by species, the number of registrations at disadvantaged settlements, the prevalence and periodicity of epizootics by area of the zone. Attention is focused on an episode associated with the possible, specific, infectious and epidemiological danger of group burials of people.
Эпизоотолого-эпидемиологический мониторинг сибирской язвы в Центральной и Южной зонах Якутии / Г. Т. Дягилев, В. Ф. Чернявский, М. Е. Игнатьева, О. Н. Софронова, О. И. Никифоров // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 98-100 — DOI: 10.25789/YMJ.2018.62.29.
DOI: 10.25789/YMJ.2018.62.29
Количество страниц: 4 с.
- Общественные науки. Образование > Право. Юридические науки > Международное право,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > ОБЩЕСТВЕННЫЕ НАУКИ > Право. Юридические науки,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина.
To evaluate the effectiveness of vasoactive therapy with synthetic somatostatin analogues at acute esophageal variceal bleeding in patients with hepatic cirrhosis with portal hypertension syndrome a retrospective analysis of the results of a comprehensive treatment of patients with cirrhosis and portal hypertension syndrome was done. The presented clinical experience of the use of synthetic somatostatin analogues in complex therapy at acute esophageal variceal bleeding allows recommending their wide use in the practice of urgent surgical clinics.
Опыт применения синтетических аналогов соматостатина при кровотечениях из варикозно расширенных вен пищевода у больных циррозом печени с синдромом портальной гипертензии в многопрофильном хирургическом Центре Республики Саха (Якутия) / В. В. Савельев, М. М. Винокуров, В. П. Егорова, Т. В. Ялынская // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 90-92 — DOI: 10.25789/YMJ.2018.62.27.
DOI: 10.25789/YMJ.2018.62.27
Количество страниц: 4 с.
We studied the specific weight of biliary pancreatitis in the structure of patients with cholelithiasis. Based on the results of the studies, the cause of the occurrence of biliary pancreatitis – cholelithiasis and its diagnostic signs in the form of rapidly increasing hyperbilirubinemia and an increase in the level of ALT with a history for more than 20 years is proved.
Желчнокаменная болезнь как причина острого билиарного панкреатита / Т. М. Тяптиргянова, А. В. Тобохов, А. Д. Макаров, З. А. Яковлева // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 82-84 — DO: 10.25789/YMJ.2018.62.24.
DOI: 10.25789/YMJ.2018.62.24
Количество страниц: 4 с.
The authors assessed the effectiveness of using of the combination of a hepatoprotector phosfogliv and immunomodulator cycloferon on the state of functional and morphological parameters of microcirculation in patients with non-alcoholic steatohepatitis (NASH) after infectious mononucleosis (IM). It is revealed that using the combination of hepatoprotector phosphogliv and immunomodulator cycloferon in patients with NASH after infectious mononucleosis authentically significantly improves parameters of microcirculation, eliminates of the phenomena of stasis and sludge syndrome in the arterioles and capillaries, and accelerates blood circulation in comparison with standard treatment of patients.
Динамика функциональных и морфологических показателей микрогемоциркуляции у больных с неалкогольным стеатогепатитом вследствие перенесенного инфекционного мононуклеоза / А. В. Хабарова, Я. А. Соцкая // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 85-88 — DO: 10.25789/YMJ.2018.62.25.
DOI: 10.25789/YMJ.2018.62.25
Количество страниц: 4 с.
Autosomal recessive deafness type 1A is one of the most frequent hereditary diseases in the Republic Sakha (Yakutia). The revealed features of the spectrum and frequency of pathogenic variants in the GJB2 gene in patients with congenital hearing impairment allow introducing routine DNA diagnostics into medical practice. The article discusses some of the bioethical issues of DNA testing of autosomal recessive deafness 1A type.
Некоторые биоэтические вопросы молекулярно-генетической диагностики аутосомно-рецессивной глухоты 1А типа, распространенной в якутской популяции / С. К. Кононова, Н. А. Барашков, В. Г. Пшенникова, А. В. Соловьев, А. М. Чердонова, А. А. Никанорова, Г. П. Романов, Э. К. Хуснутдинова, С. А. Федорова, Ф. М. Терютин // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 79-82 — DO: 10.25789/YMJ.2018.62.23.
DOI: 10.25789/YMJ.2018.62.23
Количество страниц: 4 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Лекарствоведение. Фармакология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Анатомия. Физиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина.
Morphometric changes in the seminal vesicles of rats of the reproductive period under conditions of prolonged systemic immunosuppression were studied. Reliable changes in the organometric parameters of the organ were detected both at the early (7, 15 days) and at the later periods of observation, which indicates the direct effect of cyclophosphamide on the biosynthetic processes in the organ. Micromorphometric changes, as well as the results of cyto– and karyometry, confirm the organometric data and indicate the development of local disorders in the morphogenesis of seminal vesicles caused by the dysregulation of the endocrine-immune organ homeostasis.
Измерения строения семенных пузырьков крыс репродуктивного периода в условиях циклофосфамид-индуцированной иммуносупрессии / С. А. Кащенко, А. А. Захаров // Якутский медицинский журнал. — 2018. — N 2 (62). — С. 76-78 — DO: 10.25789/YMJ.2018.62.22.
DOI: 10.25789/YMJ.2018.62.22
Количество страниц: 4 с.
The effect of dihydroquercetin (DHA) bioflavonoid in a dose of 50 mg/kg on DNA synthesis and the state of the nucleo-nucleolar apparatus of white rat cardiomyocytes on an intact background and under conditions of oxidative stress was studied. The corrective effect of DHA on biosynthetic processes in the myocardium of white rats in the presence of oxidative stress was revealed. The effect of DHA on an intact background inhibits DNA synthetic processes in the myocardium of newborn animals and reduces the size of nuclei and nucleoli in cardiomyocytes of sexually mature animals. The obtained data make it possible to recommend the use of antioxidants in cardiology only in the presence of pronounced oxidative stress.
Биосинтетические процессы в кардиомиоцитах белых крыс после введения биофлавоноида дигидрокверцетина / Е. Н. Сазонова, Д. В. Яковенко, О. А. Лебедько, А. Ю. Марочко, С. Л. Жарский, В. А. Добрых, М. Ф. Рзянкина, Т. В. Чепель // Якутский медицинский журнал. — 2019. — N 4 (68). — С. 109-112 – DO:10.25789/YMJ.2018.63.36.
DOI: 10.25789/YMJ.2018.63.36