Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Организация здравоохранения и общественное здоровье,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Педиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Организация здравоохранения и общественное здоровье,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Педиатрия.
This article is devoted to peculiarities of forming motherhood in 15-19-year-old girls in the republic.. The data of empirical research performed on school and student sample Yakutsk, Churapcha’s schools are presented (n = 86; girls in the age of 15-19 years). For studying of representations of motherhood interrogation was applied. Results of the interrogation showed that the most important principle of the role of the motherhood, is formation of readiness at girls - future mothers before occurrence at them of the children. Given researches testify of low level of readiness of girls of school and student youth to the motherhood. Applied aspect of under study problem can be realized in the organization of volunteering among students, interns (MI NEFU) on increase of knowledge and propagation of the motherhood, breastfeeding, sexual literacy, chastity, monogamous marriage in Sakha (Yakutia) Republic educational establishments
Алексеева, С. Н. К вопросу формирования материнства у девушек 15-19 лет в условиях отдельного региона (на примере Республики Саха (Якутия) / С. Н. Алексеева, Т. В. Хомподоева // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 3 (12). — С. 43-47.
Количество страниц: 10 с.
This review article presents a modern concept of vitamin D metabolism, which is a seco-steroid prohormone. For many years, it was believed that the main action of vitamin D was to provide calcium-phosphorus homeostasis. Hormone-active metabolite of vitamin D - calcitriol 1, 25 (OH)2D has a pleiotropic effect, which is realized through the vitamin D receptors (VDR), located in the target organs: bones, muscles, intestines, kidneys, heart, prostate, mammary glands, pancreas, immune system. The VDR gene has a high variability of polymorphic sequences. Of the more than 30 known single nucleotide sequences, the most studied are ApaI (rs7975232), BsmI (rs1544410), FokI (rs2228570), TaqI (rs731236) and Cdx2 (rs11568820). In recent years, the results of multicenter, cohort studies, which investigated the role of VDR polymorphism in the development of pathology of various human organs and systems. The prevalence of VDR alleles polymorphism has ethnic differences
На заметку клиницисту: современный взгляд на метаболизм витамина Д и полиморфизм гена рецептора витамина Д / А. И. Пальшина, С. Г. Пальшина, С. Л. Сафонова, В. Г. Пальшин // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 3 (12). — С. 34-42.
Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Гигиена. Санитария,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Пульмонология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Гигиена. Санитария,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Пульмонология.
Pertussis remains an urgent problem of children’s infectious pathology. Children of early age continue to form a group threatened to develop severe and complicated forms of the disease, which can lead to fatal outcomes. Although for many years the pertussis clinic has been well studied, the correct diagnosis is established untimely, which causes errors in treatment and significantly affects the outcome of the disease. In conditions of wide dissemination of pertussis, preservation, mortality, and given the low level of diagnostics, remains an urgent development of clinical criteria for the diagnosis of various forms of whooping cough, especially in children of early age. The article presents a clinical case of pertussis in a one-month-old child. The diagnosis was made on the basis of anamnestic, clinical, laboratory and instrumental data. The main indicator was a positive test for IgM Bordetella pertussis in the mother, while in the child it was negative
Маркова, С. В. Клинический случай коклюша / С. В. Маркова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 3 (12). — С. 29-33.
Количество страниц: 8 с.
With increasing incidence of pulmonary tuberculosis with multiple drug resistance of Mycobacterium tuberculosis, the problem of adequate treatment of newly diagnosed patients has become more urgent. In this case, treatment must be carried out in a specialized hospital in strict accordance with the Federal Clinical Recommendations for diagnosis and treatment of pulmonary tuberculosis with multiple drug resistance of the causative agent (2014). One of the effective methods in the complex treatment of drug-resistant pulmonary tuberculosis is the endoscopic bronchial valve placement (EBVP), based on the creation of hypoventilation in the affected area of the lung by inserting an endobronchial valve into the lumen of the bronchus. The article shows the experience of using the method for 7 years in the PhthisiologyResearch Center. A total of 102 endoscopic bronchial valve placementswere performed, with 29 of them on a quota for high-tech medical care; and the EBVPmethodproved to be highly efficient. The given four clinical cases of an integrated treatment demonstrate high clinical and radiological effectiveness of using EBVPfor the infiltrative, disseminated pulmonary tuberculosis; and one casehad a relatively unfavorable outcome of the endoscopic bronchial valve placement
Эффективность применения клапанной бронхоблокации в комплексном лечении больных туберкулезом органов дыхания / А. С. Делахов, А. Ф. Кравченко, Е. С. Павлова, А. А. Тарасова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 3 (12). — С. 22-28.
Количество страниц: 6 с.
The problem of autoimmune diseases is relatively young, about 50 years, but despite the short period, it has become the most relevant in modern clinical neurology. A special place among the demyelinating autoimmune disease is neuromyelitis optica. Neuromyelitis optica the second most frequent form of inflammatory, autoimmune, demyelinating disease after multiple sclerosis. In the last decade, the scientific understanding of Devic’s disease has expanded significantly. Neuromyelitis optica refers to rare, demyelinating diseases of the nervous system, while in the literature there is no precise data on the incidence and prevalence of the disease. To date, information about epidemiology is based on the results of individual studies. It is known, that the disease is more often diagnosed among people of Asian descent, in all populations women are more often ill. Neuromyelitis optica, unlike other demyelinating diseases, has a severe progressive course and quickly leads to persistent disability. To date, with the isolation of a specific marker (NMO-IgG), there are opportunities for an accurate diagnosis. This article presents a case of a recurring course of opticoneuromyelitis meeting the known diagnostic criteria, including the determination of aquaporin-4 antibodies of aquaporin 4 in serum. Timely diagnosis of the disease, taking into account some clinical features, using immunological methods (determination of oligoclonal antibodies, determination of the level of aquaporin-4 antibodies), instrumental methods (especially MRI in neuromyelitis optica), timely adequate treatment, will help reduce the likelihood of irreversible neurological deficit
Оптиконейромиелит: клиническое наблюдение / Н. Ю. Горохова, Т. Я. Николаева, Т. Е. Попова, Л. Т. Оконешникова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 3 (12). — С. 17-21.
Количество страниц: 6 с.
In the period 2003-2016, 6 patients with a diagnosis of megaloblastic anemia passed through the Oncology Department of the Pediatric Center (PDT) of the Republic’s Hospital 1- National Center of Medicine. The average age of children was 13 years. In the clinical picture, pronounced anemic syndrome prevailed. On the part of the gastrointestinal tract, inflammatory changes predominated, in the form of esophagitis, gastritis, duodenitis. One boy hadatrophic gastritis. Changes in the nervous system, in the form of numbness of the fingers and toes, were present only in one girl. The patients’ hemograms showed hyperchromic anemia of severe degree, leukopenia, and thrombocytopenia. In 3 children, the level of folate was determined; in 4 children - the activity of vitamin B12 in serum; in 2 - the level of folate was lower than normal; with the activity of vitamin B12 low in all the examined. Two children were assessed for the level of folate red blood cells, which also turned out to be below normal. According to the survey, a combination deficit of vitamin B12 and folic acid was found in two patients. The cause of megaloblastic anemia was insufficient nutrition (rejection of animal products), diphyllobothriasis, and atrophic gastritis. In three children, the cause of anemia remained unclear. With timely diagnosis and adequate therapy, taking into account the underlying cause, this disease can be treated with a favorable prognosis
Мегалобластные анемии у детей / Е. Ф. Аргунова, С. А. Кондратьева, О. В. Ядреева, Н. Н. Протопопова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 3 (12). — С. 12-16.
Количество страниц: 6 с.
Parkinson’s disease and essential tremor are the most common neurodegenerative diseases, which are accompanied by the development of tremor - involuntary rhythmic hyperkinesis. In the essential tremor,tremor has a kinetically postural character with a frequency of 6 to 10 Hz, affectingarms, head, face, vocal cords, tongue, legs and trunk. Parkinson tremor has a frequency of 4-6 Hz, occurring at rest in the form of “counting coins” or “rolling pills”, decreasing with active movements until complete disappearance, and is characterized by resumption after 2 or more seconds after giving the pose (“renewed” tremor). The generation of tremors is associated with dysfunction of two main ways: basal nuclei - cerebellum - thalamus and cogwheel - olive complex. Consequently, damage to any of these levels leads to the development of tremors. Recently, the concept of a single continuum of essential tremor - Parkinson’s disease - is widely discussed.It has been established that these neurological disorders can coexist or transit into each other. So, essential tremor increases the risk of developing Parkinson’s disease by 3.5 times, and in patients with Parkinson’s disease the likelihood of attaching an essential tremor is as high. This is due to the cross pathophysiological mechanism, which is probably due to genetic mutations. This article discusses the pathophysiological mechanisms of the development of tremor in patients with Parkinson’s disease and essential tremor. We describe a patient with the essential tremor whose disease has been transformed into tremor predominant Parkinson’s disease
Таппахов, А. А. Взаимосвязь болезни Паркинсона и эссенциального тремора: обзор литературы и клинический случай /А. А. Таппахов, Т. Г. Говорова, Т. Е. Попова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 2 (11). — С. 44-49.
Количество страниц: 6 с.
The article is devoted to the epidemiology and specific prevention of hepatitis A in the Republic of Sakha (Yakutia). It presents the data on the incidence of hepatitis A for the period 2000-2017. It is shown that vaccination against hepatitis A is the most effective strategy to control this infection in modern conditions. The aim of this work was to assess the epidemiological situation with hepatitis A in the Republic of Sakha (Yakutia). Materials and methods. The paper uses the materials of official statistics of the Territorial administration of Rospotrebnadzor of the Republic of Sakha (Yakutia) and the data of the Department for the treatment of patients with viral hepatitis SBU RS (I) “Yakutsk City Clinical Hospital”. Conclusions and results. As a result of selective immunization of risk groups over the past decades, the republic has managed to reduce the incidence of viral hepatitis A in general. However, in 2017, 34 cases of viral hepatitis A were registered; compared to the previous year, the incidence rate increased by 3.8 times. The incidence rate was 3.54 per 100 thousand population, which is 1.5 times lower than the average of Russia (5.52 per 100 thousand population). Also, routine vaccination against viral hepatitis A in children aged 20 months within the regional calendar of preventive vaccinations continues. With the increase in the number of vaccinated against hepatitis A, the incidence fell to occasional cases
Эпидемиологическая ситуация по гепатиту А и его специфическая профилактика в Республике Саха (Якутия) / В. К. Семенова, В. В. Иванова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 2 (11). — С. 55-59.
Количество страниц: 8 с.
In accordance with the task set, the incidence of the population in Verkhnevilyuysky, Verkhoyansky, Tattinsky and Even-Bytantaiskydistricts of the Republic of Sakha (Yakutia) for 2006-2016 was analyzed. At the same time, the general and primary morbidity of both the general population and the age range was considered in adults and children (0-14 years) of the population. According to official and departmental statistics, the analysis was carried out according to the percential method, first as a whole in the republic, then on the selected districts. Thus, the incidence rate for these districts is positioned in comparison with the indicators of all administrative-territorial entities of the Republic of Sakha (Yakutia). It turns out that in the Verkhnevilyuysky, Verkhoyansky, Tattinsky and Even-Bytantaisky uluses, the situation with general and primary morbidity is generally favorable both for the whole population and for the age aspect (in the adult and children’s population)
Тимофеев, Л. Ф. Заболеваемость населения в Верхневилюйском, Верхоянском, Таттинском и Эвено-Бытантайском улусах Республики Саха (Якутия) / Л. Ф. Тимофеев, Н. В. Саввина, А. Л. Тимофеев // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 2 (11). — С. 64-70.
Количество страниц: 4 с.
The analysis of the incidence rate for the period 2007-2016 was carried out. (in the age aspect - since 1992) in the Southern Economic Zone of the Republic of Sakha (Yakutia), which included Aldan and NeryungriDistricts. According to the medical and geographical zoning, these municipalities are part of the southern group of districts. At the same time, the general and primary morbidity of both the general population and in the age range in adults and children (0-14 years) of the populationwas considered. According to official and departmental statistics, the analysis was carried out according to the percentile method, first as a whole in the republic, then on the selected districts. Thus, the incidence rate for these districtsis positioned in comparison with the indicators of all administrative-territorial entities of the Republic of Sakha (Yakutia). It turns out that in the Southern economic zone the situation with the general and primary morbidity is favorable for the whole population and the adult population as a whole. However, there is a tendency to worsen the situation of the children’s population, which should not disturb the pediatric service of Aldan and Neryungri Central District Hospitals
Заболеваемость населения в Южной экономической зоне Республики Саха (Якутия) / Л. Ф. Тимофеев, П. Г. Петрова, Н. В. Борисова [и другие] // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 2 (11). — С. 60-63.