Место работы автора, адрес/электронная почта: Северо-Восточный федеральный университет им. М. К. Аммосова, Медицинский институт ; 677013, г. Якутск, ул. Ойунского, 27, каб. 215 ; e-mail: vb.egorova@s-vfu.ru, veraborisovna@yandex.ru ; https://www.s-vfu.ru/
Ученая степень, ученое звание: канд. мед. наук
Область научных интересов: Неонатология, профилактическая медицина
ID Автора: РИНЦ AuthorID: 563048
Деятельность: В 1998-2000 г. проходила клиническую ординатуру на базе Московской медицинской академии им. И. М. Сеченова. С 2000 г. работает в Якутском государственном университете им. М. К. Аммосова.
Количество страниц: 10 с.
Егорова, В. Б. Социальные и медико-демографические аспекты состояния здоровья подростков в Республике Саха (Якутия) / В. Б. Егорова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия "Медицинские науки". – 2018. – N 3 (12). – C. 57-65. – DOI: 10.25587/SVFU.2018.3(13).18853
DOI: 10.25587/SVFU.2018.3(13).18853
Количество страниц: 6 с.
Егорова, В. Б. Клинический случай врождённого гипотиреоза у новорождённого / В. Б. Егорова, В. П. Афанасьева, Н. А. Потапова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия "Медицинские науки". – 2020. – N 4 (21). – C. 35-39. – DOI: 10.25587/SVFU.2020.21.4.006
DOI: 10.25587/SVFU.2020.21.4.006
Количество страниц: 4 с.
The article presents 2 clinical cases of congenital central hypoventilation (CCHS) in children in the Republic Sakha (Yakutia). The first case is a child born in 2016; the diagnosis was confirmed at 7 months of age. The second case is a child born in 2018; the diagnosis was confirmed before 1 month of life. In clinical practice, there is often a hypodiagnosis of this disease, which explains the rarity of its definition. Taking into account clinical manifestations and depending on their intensity, early diagnosis prevents undesirable consequences of hypoxia and hypercapnia episodes, provides proper control over asphyxia episodes and determines the disease prognosis. Since CCHS usually manifests itself in the neonatal period and mimics a multitude of diseases, differential diagnosis requires the elimination of a variety of conditions accompanied by alveolar hypoventilation, including congenital myasthenia, a number of myopathies, diaphragm dysfunction, various lung and heart defects
Случаи синдрома врожденной центральной гиповентиляции в Якутии / С. Н. Алексеева, В. Б. Егорова, Г. Б. Ушакова [и другие] // Якутский медицинский журнал. — 2020. — N 1 (69). — С. 121-124. – DOI: 10.25789/YMJ.2020.69.31.
DOI: 10.25789/YMJ.2020.69.31
Количество страниц: 6 с.
Congenital hypothyroidism (CH), a violation of the secretion of thyroid hormones, is one of the most common congenital diseases of the endocrine glands, leading to severe disability without timely diagnosis and treatment. The incidence of CH ranges from 1 case per 4000-5000 newborns in Europe and North America to 1 case per 6000-7000 newborns in Japan. In addition, in children with the Down syndrome, the risk of developing CH is 35 times higher compared to the general population. In girls, the disease occurs 2-2.5 times more often than in boys. Currently, there is no doubt that CH in its prevalence and medico-social significance occupies an important place among childhood endocrine pathologies. The neonatal screening program for the determination of congenital hypothyroidism allows for early diagnosis and adequate treatment of children, which can help to avoid complications associated with a lack of hormones. Most newborns have no hypothyroidism clinic at birth because maternal hormones even in late pregnancy penetrate the placenta, and cord blood contains from 25 to 50 % of hormones of maternal origin. Most often, the clinical picture of congenital hypothyroidism in newborns develops gradually and is not clearly manifested in all children in the neonatal period. If obvious symptoms are noted already in the first week of life, a severe form of hypothyroidism due to aplasia or severe thyroid hypoplasia can be suspected. Hypothyroidism due to moderate hypoplasia, ectopia of the thyroid gland, or hormonal abnormalities may not have clinical manifestations during the neonatal period and may even manifest after 2-6 years of age. Screening programs may skip cases of congenital hypothyroidism (early discharge, laboratory error, severe illness, prematurity, low birth weight, transfer to another hospital, etc.), therefore, with clinical signs of hypothyroidism, a second hormonal examination is necessary. This article presents a clinical case of congenital hypothyroidism in a newborn baby in the Sakha Republic (Yakutia)
Егорова, В. Б. Клинический случай внутри врожденного гипотиреоза у новорожденного / В. Б. Егорова, В. П. Афанасьева, Н. А. Потапова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2020. — N 4 (21). — С. 35-39.
DOI: 10.25587/SVFU.2020.21.4.006
Количество страниц: 10 с.
The article is devoted to actual problems of Pediatrics and Infectology. Despite significant progress in the treatment of hepatotropic viral infections has not yet developed reliable methods of treatment of this pathology. Peg-interferons are the basis etiological treatment of chronic hepatitis. In children, the use of these drugs was permitted, only in 2011. The study group included 50 children and adolescents with chronic hepatitis treated with antiviral therapy. The first group included 24 patients with chronic hepatitis B. The second group included 26 patients with chronic hepatitis C. The study used clinical, immunological methods, technology in molecular biology and instrumental methods of research. The results obtained were processed using statistical methods binary regression and survival analysis. Our experience in the treatment of chronic hepatitis B in children, allows you to identify the most effective treatment regimen. As a result, long-term follow-up after treatment identified factors that influence the effectiveness of treatment and the preservation of the results. Positive predictors of effectiveness causal treatment of viral hepatitis are immunological parameters, and in chronic hepatitis C - the ethnic factor. According to our data patients effectiveness of treatment of chronic hepatitis B does not exceed 30 %, whereas in chronic hepatitis C was 80 %. Duration of preservation of stable remission after closure of antiviral therapy, in patients with chronic hepatitis dependent on sex of the patient and the viral load prior to treatment. The implementation in practice of the standard treatment of chronic hepatitis C, comprising a combination of peg-INFα-2b and Ribavirin, allowed to achieve maximum effectiveness of antiviral therapy. Accounting predictors of treatment effectiveness and the preservation of the results will more accurately predict the long-term results of antiviral therapy in children and adolescents with chronic hepatitis
Лечение хронических гепатитов у детей и подростков в Якутии (тактика, эффективность, прогноз)/ Т. Г. Дмитриева, Я. А. Мунхалова, В. Б. Егорова [и другие] // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2016. — N 4 (09). — С. 5-13.
Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Педиатрия,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Неврология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Педиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Неврология.
Сравнительный анализ клинической картины детей рожденных с синдромом Дауна / С. Н. Алексеева, В. Б. Егорова, Е. В. Трофимова [и другие] // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2019. — N 3 (16). — С. 35-40.— DOI: 10.25587/SVFU.2019.3 (16).39465
DOI: 10.25587/SVFU.2019.3(16).39465
Количество страниц: 6 с.
Егорова, В. Б. Часто болеющие дети: клинические особенности и микробиоценоз верхних дыхательных путей / В. Б. Егорова, М. П. Черкашин, А. Ю. Колмакова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2019. — N 2 (15). — С. 43-47.— DOI: 10.25587/SVFU.2019.2 (15).31311
DOI: 10.25587/SVFU.2019.2(15).31311
Количество страниц: 4 с.
Клинический случай врожденного порока сердца: перерыв дуги аорты / С. Н. Алексеева, В. Б. Егорова, И. П. Говорова, В. М. Константинова, Н. И. Дуглас, С. Г. Ксенофонтова // Якутский медицинский журнал. — 2020. — N 3 (71). — С. 131-133. – DOI: 10.25789/YMJ.2020.71.33.
DOI: 10.25789/YMJ.2020.71.33
Количество страниц: 4 с.
The authors have presented the results of their study of the features of the epidemiological process and the clinical picture in children and adolescents with chronic hepatitis B (CHB), representatives of the Mongoloid race. A comparative analysis of the data of patients of Mongoloid and Caucasoid races (Yakuts, representatives of small indigenous peoples of the North, Russians residing in the territory of Yakutia) is carried out. The researchers have found out that in children and adolescents of the Mongoloid race the CHB morbidity is significantly higher, there is a tendency to a more severe course of the disease than in the representatives of the Caucasoid race.
Хронический гепатит В у детей и подростков представителей монголоидной расы / Т. Г. Дмитриева, А. О. Острелина, В. Б. Егорова, Я. А. Мунхалова, О. Н. Иванова, С. Н. Алексеева // Якутский медицинский журнал. — 2018. — N 3 (63). — С. 60-63 — DOI: 10.25789/YMJ.2018.63.20.
DOI: 10.25789/YMJ.2018.63.20
Количество страниц: 3 с.
The article presents the results of the study of the etiological, clinical features of secondary pyelonephritis in children, depending on the type of abnormalities of kidney and urinary tract development. We’ve revealed that secondary pyelonephritis most often develops against the background of neurogenic dysfunction of the bladder and vesicoureteral reflux. In this case, children more often recorded neurogenic dysfunction of the bladder in a hyporeflective type. And among children with vesicoureteral reflux, the prevalence of vesicoureteral reflux on the left was more often noted. The main complication of secondary pyelonephritis is reflux-nephropathy with the development of chronic renal failure. Recently, the concept of obstruction of the urinary tract has undergone significant changes and has become more capacious.
Этиологические, клинические особенности вторичного пиелонефрита у детей / Я. А. Мунхалова, В. Б. Егорова, С. Н. Алексеева, Т. Г. Дмитриева, О. Н. Иванова, А. П. Коркина // Якутский медицинский журнал. — 2018. — N 3 (63). — С. 40-42
DOI: 10.25789/YMJ.2018.63.12